Articles/HTTP

HTTP 421 Misdirected Request — What It Means

What HTTP status code 421 Misdirected Request means, when servers return it, and how to handle it correctly.

Published September 25, 2026

HTTP 421 Misdirected Request — The request was sent to a server that can't produce a response for it.

Key points

  • Happens when a connection is reused for a domain the server is not configured to serve
  • Common in HTTP/2 setups where multiple domains share one connection
  • Resolved by fixing server routing or virtual host configuration
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